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Application SolutionsPyruvylation
Lysine pyruvylation (Kpy) is a metabolite-associated modification derived from pyruvate, a central intermediate of glycolysis.
Application SolutionsGlutarylation
Lysine glutarylation (Kglu) is a reversible lysine acylation modification derived from glutaryl-CoA.
Application SolutionsLeucylation
Lysine leucylation (KLeu) represents a unique connection between amino acid metabolism and protein modification.
Application SolutionsFumarylation
Lysine fumarylation (Kfu) is a recently identified PTM first characterized in Escherichia coli.
Application SolutionsMethacrylation
Lysine methacrylation (Kmea) is a new type of posttranslational modification and a structural isomer of crotonyllysine (Kcr).
Application SolutionsItaconate-Mediated Modifications
Itaconate is an immunometabolite that drives two distinct protein modifications: cysteine itaconation (S-itaconation) and lysine itaconylation (K-itaconylation).
Application SolutionsProtein Citrullination
Protein citrullination is an irreversible PTM that converts arginine residues to citrulline through peptidyl arginine deiminases (PADs).
Application SolutionsS-Nitrosylation
S-Nitrosylation involves the reversible attachment of nitric oxide (NO) to cysteine thiols, forming S-nitrosothiols (SNOs).
Application SolutionsCarboxyethylation
Carboxyethylation includes two distinct types of protein modifications with different mechanisms and biological functions.
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