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B Cell Activation

B cells primarily recognize antigens through the B-cell receptor (BCR) and initiate intracellular signaling cascades.

Topic

T Cell Activation

T-cell activation is a central process in adaptive immune responses.

Topic

Origin and Differentiation of Immune Cells

Hematopoietic stem cells (HSCs) are the fundamental cellular source responsible for the generation and maintenance of immune cells.

Topic

Myeloid Immune Cells

Myeloid immune cells encompass macrophages, DCs and granulocytes. They drive innate immune responses, execute pathogen elimination, inflammation and tissue homeostasis.

Topic

Lymphoid Immune Cells

Lymphoid immune cells including T, B and NK cells bridge innate and adaptive immunity, mediating pathogen clearance, anti‑tumor defense and immune homeostasis.

Topic

Overview of Immune Cells

Immune cells are essential functional cells that maintain immune defense and immune homeostasis in the body. They play central roles in infection defense, inflammation regulation, tumor immunity, tissue repair, and the study of immune-related diseases.

Topic

Hematological CSCs

Hematological Cancer Stem Cells (HCSCs) are a distinct population of cells present in hematological malignancies that possess key stem cell-like properties, including self-renewal, long-term persistence, disease-initiating capacity, and therapy resistance.

Topic

Solid Tumor CSCs

Solid Tumor Cancer Stem Cells (Solid Tumor CSCs) are a specialized subpopulation of cells present in various solid tumors that possess self-renewal capacity, differentiation potential, and tumor-initiating ability.

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