U-Blot® NCPR Rabbit mAb

Background：This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors , FAD and FMN , which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases , including apparent combined P450C17 and P450C21 deficiency , amenorrhea and disordered steroidogenesis , congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq , Jul 2008] ,