- Target
- CENPE
- Reactivity
- Human
- Application
- WB,IF,ELISA
- MW(Calculated)
- 316kD
- MW(Observed)
- 270kD
- Host Species
- Rabbit
- Isotype
- IgG, Kappa
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year (Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- PT1850R
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- CENPE
- Protein Name
- Centromere-associated protein E (Centromere protein E) (CENP-E) (Kinesin-related protein CENPE)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 1062
- SwissProt-1
- Q02224
- Organism-2
- Mouse
- Gene ID-2
- 229841
- SwissProt-2
- Q6RT24
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Chromosome , centromere , kinetochore . Cytoplasm , cytoskeleton , spindle . Chromosome , centromere . Associates with kinetochores during congression (as early as prometaphase) , relocates to the spindle midzone at anaphase , and is quantitatively discarded at the end of the cell division (By similarity) . Recruited to the kinetochore in a SEPT7 , CENPQ and TRAPPC12-dependent manner (PubMed:18460473 , PubMed:25918224 , PubMed:25395579) . Recruited to the pericentromeric/centromeric regions of the chromosome in a CTCF-dependent manner (PubMed:26321640) . .