U-Blot® IRS2 Rabbit mAb

Background：This gene encodes the insulin receptor substrate 2 , a cytoplasmic signaling molecule that mediates effects of insulin , insulin-like growth factor 1 , and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation , as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. [provided by RefSeq , Jul 2008] ,