U-Blot® ABCG1 Rabbit mAb

Background：The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 , MDR/TAP , MRP , ALD , OABP , GCN20 , White) . This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport , and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq , Jul 2008] ,