- Target
- PI 3-Kinase p110δ
- Reactivity
- Human,Mouse,Rat
- Application
- WB,IHC,IF,ELISA
- MW(Calculated)
- 119kD
- MW(Observed)
- 119kD
- Host Species
- Rabbit
- Isotype
- IgG,Kappa
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- PT1732R
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- PIK3CD
- Protein Name
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
- Other Name
- PIK3CD;Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform;PI3-kinase subunit delta;PI3K-delta;PI3Kdelta;PtdIns-3-kinase subunit delta;Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta;PtdIns-3-kinase subunit p110-delta;p110delta
- Organism-1
- Human
- Gene ID-1
- 5293
- SwissProt-1
- O00329
- Organism-2
- Mouse
- Gene ID-2
- 18707
- SwissProt-2
- O35904
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- In humans, the highest levels of expression are seen in peripheral blood mononuclear cells, spleen, and thymus, and low levels of expression in testes, uterus, colon, and small intestine but not in other tissues examined including prostate, heart, brain, and liver (PubMed:9235916). Isoform 2 is expressed in normal thymus, lung and spleen tissues, and is detected at low levels in normal lysates from colon and ovarian biopsies, at elevated levels in lysates from colorectal tumors and is abundantly expressed in some ovarian tumors (at protein level). Both isoform 1 and isoform 2 are widely expressed. Isoform 1 is expressed predominantly in leukocytes.