U-Blot® PABP1 Rabbit mAb

U-Blot® PABP1 Rabbit mAb
U-Blot® PABP1 Rabbit mAb
$268.00
Size:50μL
SKU: WR5163-50

Catalog No.: WR5163

Specification: 50μL/100μL

Stock: In stock

U-Blot® PABP1 Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010],

Product Overview

Catalog No.
WR5163
SKU
WR5163-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
PABP1
Reactivity
Human,Mouse,Rat
Application
WB,IHC,IF,IP,ELISA
MW(Calculated)
71kD
MW(Observed)
71kD
Host Species
Rabbit
Isotype
IgG,Kappa
Conjugate/Modification
Unmodified
Modification site
--
Recommended Dilution Ratio
IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
Monoclonal
Clone No.
PT1397R
Immunogen
--
Sequence
--
Specificity
Endogenous
Gene Name
PABPC1 PAB1 PABP1 PABPC2
Protein Name
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Other Name
--
Organism-1
Human
Gene ID-1
26986
SwissProt-1
P11940
Organism-2
Mouse
Gene ID-2
--
SwissProt-2
P29341
Organism-3
Rat
Gene ID-3
--
SwissProt-3
Q9EPH8
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Cytoplasm . Cytoplasm, Stress granule . Nucleus . Cell projection, lamellipodium . Localized in cytoplasmic mRNP granules containing untranslated mRNAs (PubMed:17289661). Shuttles between the cytoplasm and the nucleus (PubMed:9582337). During stress and in the absence of DDX3X, localizes to the nucleus (PubMed:21883093). At the leading edge of migrating fibroblasts, colocalizes with DDX3X (PubMed:28733330). Relocalizes to cytoplasmic stress granules upon cellular stress where it colocalizes with ENDOV (PubMed:27573237). In case of HRSV infection, localizes in cytoplasmic inclusion bodies substructures called inclusion bodies associated granules (IBAGs) (PubMed:31649314). .

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

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HoursMonday-Friday 09:00-18:00 CST

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Keywords:Rabbit mAbs