- Target
- AP-2γ
- Reactivity
- Human,Mouse,Rat
- Application
- WB,IHC,IF,ELISA
- MW(Calculated)
- 49kD
- MW(Observed)
- 49kD
- Host Species
- Rabbit
- Isotype
- IgG,Kappa
- Conjugate/Modification
- Tyr397
- Modification site
- --
- Recommended Dilution Ratio
- IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- PT1333R
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- TFAP2C
- Protein Name
- Transcription factor AP-2 gamma
- Other Name
- TFAP2C;Transcription factor AP-2 gamma;AP2-gamma;Activating enhancer-binding protein 2 gamma;Transcription factor ERF-1
- Organism-1
- Human
- Gene ID-1
- 7022
- SwissProt-1
- Q92754
- Organism-2
- Mouse
- Gene ID-2
- 21420
- SwissProt-2
- Q61312
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Domain:The WW-binding motif mediates interaction with WWOX.,Function:Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.,induction:During retinoic acid-mediated differentiation.,online information:Activatin protein 2 entry,PTM:Sumoylated on Lys-10; which inhibits transcriptional activity.,similarity:Belongs to the AP-2 family.,subunit:Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members (By similarity). Interacts with WWOX. Interacts with CITED4. Interacts with UBE2I.,