- Target
- Smo
- Reactivity
- Human,Mouse,Rat
- Application
- WB,IF,IP,ELISA
- MW(Calculated)
- 86kD
- MW(Observed)
- 100kD
- Host Species
- Rabbit
- Isotype
- IgG,Kappa
- Conjugate/Modification
- Phospho
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- PT1379R
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- SMO
- Protein Name
- Smoothened homolog
- Other Name
- SMO;SMOH;Smoothened homolog;SMO;Protein Gx
- Organism-1
- Human
- Gene ID-1
- 6608
- SwissProt-1
- Q99835
- Organism-2
- Mouse
- Gene ID-2
- 319757
- SwissProt-2
- P56726
- Organism-3
- Rat
- Gene ID-3
- 25273
- SwissProt-3
- P97698
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Disease:Defects in SMO are involved in basal cell carcinoma (BCC).,Function:G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO).,similarity:Belongs to the G-protein coupled receptor Fz/Smo family.,similarity:Contains 1 FZ (frizzled) domain.,