- Target
- Lyn
- Reactivity
- Human,Mouse,Rat
- Application
- WB,IF,ELISA
- MW(Calculated)
- 59kD
- MW(Observed)
- 59kD
- Host Species
- Rabbit
- Isotype
- IgG,Kappa
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- PT1055R
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- LYN
- Protein Name
- Tyrosine-protein kinase Lyn
- Other Name
- LYN;JTK8;Tyrosine-protein kinase Lyn;Lck/Yes-related novel protein tyrosine kinase;V-yes-1 Yamaguchi sarcoma viral related oncogene homolog;p53Lyn;p56Lyn
- Organism-1
- Human
- Gene ID-1
- 4067
- SwissProt-1
- P07948
- Organism-2
- Mouse
- Gene ID-2
- 17096
- SwissProt-2
- P25911
- Organism-3
- Rat
- Gene ID-3
- 81515
- SwissProt-3
- Q07014
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,subunit:Interacts with phosphorylated LIME1 and with CD79A upon BCR activation. Interacts with Epstein-Barr virus LMP2A. Interacts with TGFB1I1. Interaction, via the SH2 and SH3, domains with MUC1 is stimulated by IL7 and, the subsequent phosphorylation increases the binding between MUC1 and CTNNB1/beta-catenin. Interacts with PPP1R15A via the SH3 domain.,tissue specificity:Expressed in primary neuroblastoma tumors.,