U-Blot® IRF3 (Phospho Ser386) Rabbit mAb

U-Blot® IRF3 (Phospho Ser386) Rabbit mAb
U-Blot® IRF3 (Phospho Ser386) Rabbit mAb
$288.00
Size:50μL
SKU: WR4533-50

Catalog No.: WR4533

Specification: 50μL/100μL

Stock: In stock

U-Blot® IRF3 (Phospho Ser386) Rabbit mAb Learn more

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Product information

Product detailsSpecificationsQ & AEducation

Background：This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],

Product Overview

Catalog No.
WR4533
SKU
WR4533-50
Category
Rabbit mAbs
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
IRF-3
Reactivity
Human
Application
WB,IF,ELISA
MW(Calculated)
47kD
MW(Observed)
60kD
Host Species
Rabbit
Isotype
IgG, Kappa
Conjugate/Modification
Phospho
Modification site
--
Recommended Dilution Ratio
WB 1:1000-1:15000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
Form
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source
--
Purification
Protein A
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
--
Clonality
--
Clone No.
PT0984R
Immunogen
--
Sequence
--
Specificity
IRF3 (Phospho Ser386) Monoclonal Antibody detects endogenous levels of IRF-3 protein only when phosphorylated at S386.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):ASsLE
Gene Name
IRF3
Protein Name
Interferon regulatory factor 3
Other Name
IRF3;Interferon regulatory factor 3;IRF-3
Organism-1
Human
Gene ID-1
3661
SwissProt-1
Q14653
Organism-2
Mouse
Gene ID-2
--
SwissProt-2
P70671
Organism-3
--
Gene ID-3
--
SwissProt-3
--
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Cytoplasm . Nucleus . Mitochondrion . Shuttles between cytoplasmic and nuclear compartments, with export being the prevailing effect (PubMed:10805757). When activated, IRF3 interaction with CREBBP prevents its export to the cytoplasm (PubMed:10805757). Recruited to mitochondria via TOMM70:HSP90AA1 upon Sendai virus infection (PubMed:25609812). .

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@mail.ucallm.com

Phone+(1)-866-986-9598

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HoursMonday-Friday 09:00-18:00 CST

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Keywords:Rabbit mAbs