- Target
- GSDMD
- Reactivity
- Human
- Application
- WB,IF,ELISA
- MW(Calculated)
- 53kD
- MW(Observed)
- 35kD
- Host Species
- Rabbit
- Isotype
- IgG,Kappa
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- PT0680R
- Immunogen
- --
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of Cleaved N-terminal GSDMD.
- Gene Name
- GSDMD
- Protein Name
- Gasdermin domain-containing protein 1,Gasdermin-D,GSDMD,GSDMD-CT,GSDMD-NT,GSDMD_HUMAN
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- --
- SwissProt-1
- P57764
- Organism-2
- --
- Gene ID-2
- --
- SwissProt-2
- --
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- [Gasdermin-D]: Cytoplasm, cytosol . Inflammasome . In response to a canonical inflammasome stimulus, such as nigericin, recruited to NLRP3 inflammasone with similar kinetics to that of uncleaved CASP1 precursor. .; [Gasdermin-D, N-terminal]: Cell membrane ; Multi-pass membrane protein . Secreted . Released in the extracellular milieu following pyroptosis. .; [Gasdermin-D, C-terminal]: Cytoplasm, cytosol .