Product information
Background:The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis; hence, it is a target for cancer therapy. [provided by RefSeq, Sep 2015],
Product Overview
- Catalog No.
- WR4459
- SKU
- WR4459-50
- Category
- Rabbit mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- PLK1
- Reactivity
- Human,Mouse,Rat
- Application
- WB,IHC,IF,IP,ELISA
- MW(Calculated)
- 68kD
- MW(Observed)
- 68kD
- Host Species
- Rabbit
- Isotype
- IgG,Kappa
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- PT0679R
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- PLK1 PLK
- Protein Name
- PLK1
- Other Name
- Serine/threonine-protein kinase PLK1;Polo-like kinase 1;PLK-1;Serine/threonine-protein kinase 13;STPK13;
- Organism-1
- Human
- Gene ID-1
- 5347
- SwissProt-1
- P53350
- Organism-2
- Mouse
- Gene ID-2
- 18817
- SwissProt-2
- Q07832
- Organism-3
- Rat
- Gene ID-3
- 25515
- SwissProt-3
- Q62673
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Nucleus
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)