Product information
Background:The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016],
Product Overview
- Catalog No.
- WP9383
- SKU
- WP9383-50
- Category
- Polyclonal antibodies
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- CD50/ICAM-3
- Reactivity
- Human
- Application
- WB,ELISA
- MW(Calculated)
- --
- MW(Observed)
- 42-60kD
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Phospho
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- The antiserum was produced against synthesized peptide derived from human CD50/ICAM-3 around the phosphorylation site of Ser518. AA range:484-533
- Sequence
- --
- Specificity
- Phospho-CD50 (S518) Polyclonal Antibody detects endogenous levels of CD50 protein only when phosphorylated at S518.
- Gene Name
- ICAM3
- Protein Name
- Intercellular adhesion molecule 3
- Other Name
- ICAM3;Intercellular adhesion molecule 3;ICAM-3;CDw50;ICAM-R;CD antigen CD50
- Organism-1
- Human
- Gene ID-1
- 3385
- SwissProt-1
- P32942
- Organism-2
- --
- Gene ID-2
- --
- SwissProt-2
- --
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Membrane; Single-pass type I membrane protein.
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)