Product information
Background:Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],
Product Overview
- Catalog No.
- WP15969
- SKU
- WP15969-50
- Category
- Polyclonal antibodies
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- Granzyme M
- Reactivity
- Human,Rat
- Application
- IHC,IF,ELISA
- MW(Calculated)
- --
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthetic peptide from human protein at AA range: 207-256
- Sequence
- --
- Specificity
- The antibody detects endogenous Granzyme M
- Gene Name
- GZMM MET1
- Protein Name
- Granzyme M (Met-1 serine protease) (Hu-Met-1) (Met-ase) (Natural killer cell granular protease)
- Other Name
- Granzyme M;Met-1 serine protease;Hu-Met-1;Met-ase;Natural killer cell granular protease;
- Organism-1
- Human
- Gene ID-1
- 3004
- SwissProt-1
- P51124
- Organism-2
- --
- Gene ID-2
- --
- SwissProt-2
- --
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Secreted. Cytoplasmic granule. Granules of large granular lymphocytes.
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)