Product information
Background:Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family. Alternatively spliced transcript variants encoding the same protein have been
Product Overview
- Catalog No.
- WP1511
- SKU
- WP1511-50
- Category
- Polyclonal antibodies
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- KCNS3
- Reactivity
- Human,Mouse
- Application
- WB,ELISA
- MW(Calculated)
- --
- MW(Observed)
- 54kD
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000;ELISA 1:5000-20000
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human protein . at AA range: 300-380
- Sequence
- --
- Specificity
- KCNS3 Polyclonal Antibody detects endogenous levels of protein.
- Gene Name
- KCNS3
- Protein Name
- Potassium voltage-gated channel subfamily S member 3 (Delayed-rectifier K(+) channel alpha subunit 3) (Voltage-gated potassium channel subunit Kv9.3)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 3790
- SwissProt-1
- Q9BQ31
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- Q8BQZ8
- Organism-3
- Rat
- Gene ID-3
- --
- SwissProt-3
- O88759
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cell membrane ; Multi-pass membrane protein . May not reach the plasma membrane but remain in an intracellular compartment in the absence of KCNB1 (PubMed:10484328). .
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)