U-Blot® RUNX3 Polyclonal Antibody

Name: U-Blot® RUNX3 Polyclonal Antibody
SKU: WP14384
Availability: InStock

$268.00

Size:50μL

SKU: WP14384-50

Catalog No.: WP14384

Specification: 50μL/100μL

Stock: In stock

U-Blot® RUNX3 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

Product Overview

Catalog No.: WP14384
SKU: WP14384-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: RUNX3
Reactivity: Human,Mouse
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 44kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human RUNX3. AA range:133-182
Sequence: --
Specificity: RUNX3 Polyclonal Antibody detects endogenous levels of RUNX3 protein.
Gene Name: RUNX3
Protein Name: Runt-related transcription factor 3
Other Name: RUNX3;AML2;CBFA3;PEBP2A3;Runt-related transcription factor 3;Acute myeloid leukemia 2 protein;Core-binding factor subunit alpha-3;CBF-alpha-3;Oncogene AML-2;Polyomavirus enhancer-binding protein 2 alpha C subunit;PEA2-alpha C;PEB
Organism-1: Human
Gene ID-1: 864
SwissProt-1: Q13761
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q64131
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Cytoplasm . The tyrosine phosphorylated form localizes to the cytoplasm. Translocates from the cytoplasm to the nucleus following TGF-beta stimulation. .