Product information
Background:Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530)-like repeats or thrombospondin (THBS; see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).[supplied by OMIM, Mar 2008],
Product Overview
- Catalog No.
- WP13571
- SKU
- WP13571-50
- Category
- Polyclonal antibodies
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- O-FucT-2
- Reactivity
- Human,Mouse
- Application
- IHC,IF,ELISA
- MW(Calculated)
- 50kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- The antiserum was produced against synthesized peptide derived from human POFUT2. AA range:361-410
- Sequence
- --
- Specificity
- O-FucT-2 Polyclonal Antibody detects endogenous levels of O-FucT-2 protein.
- Gene Name
- POFUT2
- Protein Name
- GDP-fucose protein O-fucosyltransferase 2
- Other Name
- POFUT2;C21orf80;FUT13;KIAA0958;GDP-fucose protein O-fucosyltransferase 2;Peptide-O-fucosyltransferase 2;O-FucT-2
- Organism-1
- Human
- Gene ID-1
- 23275
- SwissProt-1
- Q9Y2G5
- Organism-2
- Mouse
- Gene ID-2
- 80294
- SwissProt-2
- Q8VHI3
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Endoplasmic reticulum . Golgi apparatus . Mainly located in the endoplasmic reticulum. .
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)