Product information
Background:function:E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 C2 domain.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 2 WW domains.,subunit:Interacts with TP73.,tissue specificity:Predominantly expressed in adult brain, lung and heart.,
Product Overview
- Catalog No.
- WP13405
- SKU
- WP13405-50
- Category
- Polyclonal antibodies
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- NEDL2
- Reactivity
- Human,Mouse
- Application
- WB,ELISA
- MW(Calculated)
- --
- MW(Observed)
- 140-150kD
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- The antiserum was produced against synthesized peptide derived from human HECW2. AA range:481-530
- Sequence
- --
- Specificity
- NEDL2 Polyclonal Antibody detects endogenous levels of NEDL2 protein.
- Gene Name
- HECW2
- Protein Name
- E3 ubiquitin-protein ligase HECW2
- Other Name
- HECW2;KIAA1301;NEDL2;E3 ubiquitin-protein ligase HECW2;HECT;C2 and WW domain-containing protein 2;NEDD4-like E3 ubiquitin-protein ligase 2
- Organism-1
- Human
- Gene ID-1
- 57520
- SwissProt-1
- Q9P2P5
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- Q6I6G8
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cytoplasm . Cytoplasm, cytoskeleton, spindle .
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)