U-Blot® ML-IAP Polyclonal Antibody

Name: U-Blot® ML-IAP Polyclonal Antibody
SKU: WP13188
Availability: InStock

$268.00

Size:50μL

SKU: WP13188-50

Catalog No.: WP13188

Specification: 50μL/100μL

Stock: In stock

U-Blot® ML-IAP Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jul 2013],

Product Overview

Catalog No.: WP13188
SKU: WP13188-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: ML-IAP
Reactivity: Human,Mouse
Application: WB,IHC
MW(Calculated): --
MW(Observed): 21kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;IHC 1:50-300
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human ML-IAP. AA range:162-211
Sequence: --
Specificity: ML-IAP Polyclonal Antibody detects endogenous levels of ML-IAP protein.
Gene Name: BIRC7
Protein Name: Baculoviral IAP repeat-containing protein 7
Other Name: BIRC7;KIAP;LIVIN;MLIAP;RNF50;Baculoviral IAP repeat-containing protein 7;Kidney inhibitor of apoptosis protein;KIAP;Livin;Melanoma inhibitor of apoptosis protein;ML-IAP;RING finger protein 50
Organism-1: Human
Gene ID-1: 79444
SwissProt-1: Q96CA5
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: A2AWP0
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Cytoplasm . Golgi apparatus . Nuclear, and in a filamentous pattern throughout the cytoplasm. Full-length livin is detected exclusively in the cytoplasm, whereas the truncated form (tLivin) is found in the peri-nuclear region with marked localization to the Golgi apparatus; the accumulation of tLivin in the nucleus shows positive correlation with the increase in apoptosis.