U-Blot® MAD2 Polyclonal Antibody

Name: U-Blot® MAD2 Polyclonal Antibody
SKU: WP13050
Availability: InStock

$268.00

Size:50μL

SKU: WP13050-50

Catalog No.: WP13050

Specification: 50μL/100μL

Stock: In stock

U-Blot® MAD2 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP13050
SKU: WP13050-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: MAD2
Reactivity: Human,Mouse
Application: WB,IP,ELISA
MW(Calculated): --
MW(Observed): 25kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IP 1:200-500;ELISA 1:5000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human MAD2L1. AA range:91-140
Sequence: --
Specificity: MAD2 Polyclonal Antibody detects endogenous levels of MAD2 protein.
Gene Name: MAD2L1
Protein Name: Mitotic spindle assembly checkpoint protein MAD2A
Other Name: MAD2L1;MAD2;Mitotic spindle assembly checkpoint protein MAD2A;HsMAD2;Mitotic arrest deficient 2-like protein 1;MAD2-like protein 1
Organism-1: Human
Gene ID-1: 4085
SwissProt-1: Q13257
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q9Z1B5
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Chromosome, centromere, kinetochore. Cytoplasm . Cytoplasm, cytoskeleton, spindle pole. Recruited by MAD1L1 to unattached kinetochores (Probable). Recruited to the nuclear pore complex by TPR during interphase. Recruited to kinetochores in late prometaphase after BUB1, CENPF, BUB1B and CENPE. Kinetochore association requires the presence of NEK2. Kinetochore association is repressed by UBD. Sequestered to the cytoplasm upon interaction with isoform 3 of MAD1L1 (PubMed:19010891). .