U-Blot® IREβ Polyclonal Antibody

Name: U-Blot® IREβ Polyclonal Antibody
SKU: WP12866
Availability: InStock

$268.00

Size:50μL

SKU: WP12866-50

Catalog No.: WP12866

Specification: 50μL/100μL

Stock: In stock

U-Blot® IREβ Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:The kinase domain is activated by trans-autophosphorylation. Kinase activity is required for activation of the endoribonuclease domain.,function:Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.,PTM:Autophosphorylated.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.,similarity:Contains 1 KEN domain.,similarity:Contains 1 protein kinase domain.,

Product Overview

Catalog No.: WP12866
SKU: WP12866-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: IREβ
Reactivity: Human,Mouse
Application: IHC,IF,ELISA
MW(Calculated): 102kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human ERN2. AA range:841-890
Sequence: --
Specificity: IRE1α/β Polyclonal Antibody detects endogenous levels of IRE1α/β protein.
Gene Name: ERN2
Protein Name: Serine/threonine-protein kinase/endoribonuclease IRE2
Other Name: ERN2;IRE2;Serine/threonine-protein kinase/endoribonuclease IRE2;Endoplasmic reticulum-to-nucleus signaling 2;Inositol-requiring protein 2;hIRE2p;Ire1-beta;IRE1b
Organism-1: Human
Gene ID-1: 10595
SwissProt-1: Q76MJ5
Organism-2: Mouse
Gene ID-2: 26918
SwissProt-2: Q9Z2E3
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Endoplasmic reticulum membrane ; Single-pass type I membrane protein .