Product information
Background:IQ motif containing GTPase activating protein 1(IQGAP1) Homo sapiens This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines. [provided by RefSeq, Jul 2008],
Product Overview
- Catalog No.
- WP12861
- SKU
- WP12861-50
- Category
- Polyclonal antibodies
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- IQGAP1
- Reactivity
- Human,Mouse
- Application
- WB,IHC
- MW(Calculated)
- --
- MW(Observed)
- 190kD
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000;IHC 1:50-300
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- The antiserum was produced against synthesized peptide derived from human IQGAP1. AA range:247-296
- Sequence
- --
- Specificity
- IQGAP1 Polyclonal Antibody detects endogenous levels of IQGAP1 protein.
- Gene Name
- IQGAP1
- Protein Name
- Ras GTPase-activating-like protein IQGAP1
- Other Name
- IQGAP1;KIAA0051;Ras GTPase-activating-like protein IQGAP1;p195
- Organism-1
- Human
- Gene ID-1
- 8826
- SwissProt-1
- P46940
- Organism-2
- Mouse
- Gene ID-2
- 29875
- SwissProt-2
- Q9JKF1
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cell membrane . Nucleus . Cytoplasm . Subcellular distribution is regulated by the cell cycle, nuclear levels increase at G1/S phase (PubMed:20883816). .
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)