U-Blot® GABAB R1 Polyclonal Antibody

Name: U-Blot® GABAB R1 Polyclonal Antibody
SKU: WP12401
Availability: InStock

$268.00

Size:50μL

SKU: WP12401-50

Catalog No.: WP12401

Specification: 50μL/100μL

Stock: In stock

U-Blot® GABAB R1 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA(B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jan 2016],

Product Overview

Catalog No.: WP12401
SKU: WP12401-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: GABAB R1
Reactivity: Human,Mouse,Rat,Guinea Pig
Application: WB,IF,ELISA
MW(Calculated): --
MW(Observed): 108kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human GABBR1. AA range:891-940
Sequence: --
Specificity: GABAB R1 Polyclonal Antibody detects endogenous levels of GABAB R1 protein.
Gene Name: GABBR1
Protein Name: Gamma-aminobutyric acid type B receptor subunit 1
Other Name: GABBR1;GPRC3A;Gamma-aminobutyric acid type B receptor subunit 1;GABA-B receptor 1;GABA-B-R1;GABA-BR1;GABABR1;Gb1
Organism-1: Human
Gene ID-1: 2550
SwissProt-1: Q9UBS5
Organism-2: Mouse
Gene ID-2: 54393
SwissProt-2: Q9WV18
Organism-3: Rat
Gene ID-3: 81657
SwissProt-3: Q9Z0U4
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell projection, dendrite . Colocalizes with ATF4 in hippocampal neuron dendritic membranes (By similarity). Coexpression of GABBR1 and GABBR2 is required for GABBR1 maturation and transport to the plasma membrane (PubMed:15617512). .; [Isoform 1E]: Secreted .