Product information
Background:The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).[provided by RefSeq, Mar 2009],
Product Overview
- Catalog No.
- WP12239
- SKU
- WP12239-50
- Category
- Polyclonal antibodies
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- ERCC4
- Reactivity
- Human,Mouse
- Application
- WB,ELISA
- MW(Calculated)
- --
- MW(Observed)
- 103kD
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- The antiserum was produced against synthesized peptide derived from human XPF. AA range:801-850
- Sequence
- --
- Specificity
- ERCC4 Polyclonal Antibody detects endogenous levels of ERCC4 protein.
- Gene Name
- ERCC4
- Protein Name
- DNA repair endonuclease XPF
- Other Name
- ERCC4;ERCC11;XPF;DNA repair endonuclease XPF;DNA excision repair protein ERCC-4;DNA repair protein complementing XP-F cells;Xeroderma pigmentosum group F-complementing protein
- Organism-1
- Human
- Gene ID-1
- 2072
- SwissProt-1
- Q92889
- Organism-2
- Mouse
- Gene ID-2
- 50505
- SwissProt-2
- Q9QZD4
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Nucleus . Chromosome . Localizes to sites of DNA damage. .
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)