U-Blot® DNA pol δ Polyclonal Antibody

Name: U-Blot® DNA pol δ Polyclonal Antibody
SKU: WP12033
Availability: InStock

$268.00

Size:50μL

SKU: WP12033-50

Catalog No.: WP12033

Specification: 50μL/100μL

Stock: In stock

U-Blot® DNA pol δ Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Mar 2012],

Product Overview

Catalog No.: WP12033
SKU: WP12033-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: DNA pol δ cat
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 110 124kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human POLD1. AA range:1051-1100
Sequence: --
Specificity: DNA pol δ cat Polyclonal Antibody detects endogenous levels of DNA pol δ cat protein.
Gene Name: POLD1
Protein Name: DNA polymerase delta catalytic subunit
Other Name: POLD1;POLD;DNA polymerase delta catalytic subunit;DNA polymerase subunit delta p125
Organism-1: Human
Gene ID-1: 5424
SwissProt-1: P28340
Organism-2: Mouse
Gene ID-2: 18971
SwissProt-2: P52431
Organism-3: Rat
Gene ID-3: 59294
SwissProt-3: O54747
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Colocalizes with PCNA and POLD3 at S phase replication sites (PubMed:11595739). After UV irradiation, recruited to DNA damage sites within 2 hours, independently on the cell cycle phase, nor on PCNA ubiquitination. This recruitment requires POLD3, PCNA and RFC1-replication factor C complex (PubMed:20227374, PubMed:22801543). .