U-Blot® Cubilin Polyclonal Antibody

Name: U-Blot® Cubilin Polyclonal Antibody
SKU: WP11835
Availability: InStock

$268.00

Size:50μL

SKU: WP11835-50

Catalog No.: WP11835

Specification: 50μL/100μL

Stock: In stock

U-Blot® Cubilin Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：Cubilin (CUBN) acts as a receptor for intrinsic factor-vitamin B12 complexes. The role of receptor is supported by the presence of 27 CUB domains. Cubulin is located within the epithelium of intestine and kidney. Mutations in CUBN may play a role in autosomal recessive megaloblastic anemia. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP11835
SKU: WP11835-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Cubilin
Reactivity: Human,Rat,Mouse,
Application: IHC,IF,WB,ELISA
MW(Calculated): --
MW(Observed): 400kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from the N-terminal region of human Cubilin.
Sequence: --
Specificity: Cubilin Polyclonal Antibody detects endogenous levels of Cubilin protein.
Gene Name: CUBN
Protein Name: Cubilin
Other Name: CUBN;IFCR;Cubilin;460 kDa receptor;Intestinal intrinsic factor receptor;Intrinsic factor-cobalamin receptor;Intrinsic factor-vitamin B12 receptor
Organism-1: Human
Gene ID-1: 8029
SwissProt-1: O60494
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q9JLB4
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Apical cell membrane ; Peripheral membrane protein . Cell membrane ; Peripheral membrane protein . Membrane, coated pit . Endosome . Lysosome membrane ; Peripheral membrane protein . Lacks a transmembrane domain and depends on interaction with AMN for location at the plasma membrane (PubMed:29402915, PubMed:30523278). Colocalizes with AMN and LRP2 in the endocytotic apparatus of epithelial cells (By similarity). .