U-Blot® CLC-4 Polyclonal Antibody

Name: U-Blot® CLC-4 Polyclonal Antibody
SKU: WP11665
Availability: InStock

$268.00

Size:50μL

SKU: WP11665-50

Catalog No.: WP11665

Specification: 50μL/100μL

Stock: In stock

U-Blot® CLC-4 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：chloride voltage-gated channel 4(CLCN4) Homo sapiens The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins. [provided by RefSeq, Mar 2012],

Product Overview

Catalog No.: WP11665
SKU: WP11665-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: CLC-4
Reactivity: Human,Mouse,Rat
Application: WB,IF,ELISA
MW(Calculated): --
MW(Observed): 85kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human CLCN4. AA range:221-270
Sequence: --
Specificity: CLC-4 Polyclonal Antibody detects endogenous levels of CLC-4 protein.
Gene Name: CLCN4
Protein Name: H(+)/Cl(-) exchange transporter 4
Other Name: CLCN4;H;+;/Cl;-;exchange transporter 4;Chloride channel protein 4;ClC-4;Chloride transporter ClC-4
Organism-1: Human
Gene ID-1: 1183
SwissProt-1: P51793
Organism-2: Mouse
Gene ID-2: 12727
SwissProt-2: Q61418
Organism-3: Rat
Gene ID-3: --
SwissProt-3: P51794
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Early endosome membrane ; Multi-pass membrane protein . Late endosome membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Recycling endosome membrane ; Multi-pass membrane protein . Localizes to late endosome membrane, lysosome membrane and recycling endosome membrane in the presence of CLCN3. .