U-Blot® BinCARD Polyclonal Antibody

Name: U-Blot® BinCARD Polyclonal Antibody
SKU: WP11278
Availability: InStock

$268.00

Size:50μL

SKU: WP11278-50

Catalog No.: WP11278

Specification: 50μL/100μL

Stock: In stock

U-Blot® BinCARD Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：function:Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.,PTM:Isoform 2 is phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 CARD domain.,subcellular location:Co-expression with BCL10 induced translocation from nucleus to cytosol.,subunit:Associates with BCL10 by CARD-CARD interaction.,tissue specificity:Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain.,

Product Overview

Catalog No.: WP11278
SKU: WP11278-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: BinCARD
Reactivity: Human,Mouse
Application: IHC,IF,ELISA
MW(Calculated): 26kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human C9orf89. AA range:21-70
Sequence: --
Specificity: BinCARD Polyclonal Antibody detects endogenous levels of BinCARD protein.
Gene Name: C9orf89
Protein Name: Bcl10-interacting CARD protein
Other Name: C9orf89;Bcl10-interacting CARD protein;BinCARD
Organism-1: Human
Gene ID-1: 84270
SwissProt-1: Q96LW7
Organism-2: Mouse
Gene ID-2: 68480
SwissProt-2: Q9D1I2
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: [Isoform 1]: Nucleus . Coexpression with BCL10 induced translocation from nucleus to cytosol.; [Isoform 2]: Endoplasmic reticulum membrane ; Single-pass membrane protein . Mitochondrion membrane ; Single-pass membrane protein .