U-Blot® BCAS3 Polyclonal Antibody

Name: U-Blot® BCAS3 Polyclonal Antibody
SKU: WP11258
Availability: InStock

$268.00

Size:50μL

SKU: WP11258-50

Catalog No.: WP11258

Specification: 50μL/100μL

Stock: In stock

U-Blot® BCAS3 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：developmental stage:Fetal.,disease:A chromosomal aberration involving BCAS3 may be a cause of breast cancer. Translocation t(17;20)(q23;q13) with BCAS4.,similarity:Belongs to the WD repeat BCAS3 family.,similarity:Contains 3 WD repeats.,tissue specificity:Stomach, liver, lung, kidney, prostate, testis, thyroid gland, adrenal gland, brain, heart, skeletal muscle, colon, spleen, small intestine, placenta, blood leucocyte and mammary epithelial cells. Overexpressed in most breast cancer cell lines.,

Product Overview

Catalog No.: WP11258
SKU: WP11258-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: BCAS3
Reactivity: Human,Mouse
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 100kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:5000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from BCAS3 . at AA range: 660-740
Sequence: --
Specificity: BCAS3 Polyclonal Antibody detects endogenous levels of BCAS3 protein.
Gene Name: BCAS3
Protein Name: Breast carcinoma-amplified sequence 3
Other Name: BCAS3;Breast carcinoma-amplified sequence 3;GAOB1
Organism-1: Human
Gene ID-1: 54828
SwissProt-1: Q9H6U6
Organism-2: Mouse
Gene ID-2: 192197
SwissProt-2: Q8CCN5
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Preautophagosomal structure . Localizes in the cytoplasm in stationary cells. Translocates from the cytoplasm to the leading edge in motile cells. Colocalizes with microtubules and intermediate filaments in both stationary and motile cells (By similarity). Associates with chromatin. Recruited to estrogen receptor-induced promoters in a PELP1-dependent manner. The BCAS3:PHAF1 complex is recruited to the preautophagosomal structures adjacent to the damaged mitochondria upon mitophagy in a PRKN-PINK1 dependent manner (PubMed:33499712). .