Product information
Background:This gene encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012],
Product Overview
- Catalog No.
- WP11216
- SKU
- WP11216-50
- Category
- Polyclonal antibodies
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- ATRIP
- Reactivity
- Human,Mouse
- Application
- WB,ELISA
- MW(Calculated)
- --
- MW(Observed)
- 86kD
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- The antiserum was produced against synthesized peptide derived from human ATRIP. AA range:190-239
- Sequence
- --
- Specificity
- ATRIP Polyclonal Antibody detects endogenous levels of ATRIP protein.
- Gene Name
- ATRIP
- Protein Name
- ATR-interacting protein
- Other Name
- ATRIP;AGS1;ATR-interacting protein;ATM and Rad3-related-interacting protein
- Organism-1
- Human
- Gene ID-1
- 84126
- SwissProt-1
- Q8WXE1
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- Q8BMG1
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Nucleus . Redistributes to discrete nuclear foci upon DNA damage.
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)