U-Blot® ApoE Polyclonal Antibody

Name: U-Blot® ApoE Polyclonal Antibody
SKU: WP11078
Availability: InStock

$268.00

Size:50μL

SKU: WP11078-50

Catalog No.: WP11078

Specification: 50μL/100μL

Stock: In stock

U-Blot® ApoE Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jun 2016],

Product Overview

Catalog No.: WP11078
SKU: WP11078-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: ApoE
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 36kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human ApoE. AA range:37-86
Sequence: --
Specificity: ApoE Polyclonal Antibody detects endogenous levels of ApoE protein.
Gene Name: APOE
Protein Name: Apolipoprotein E
Other Name: APOE;Apolipoprotein E;Apo-E
Organism-1: Human
Gene ID-1: 348
SwissProt-1: P02649
Organism-2: Mouse
Gene ID-2: 11816
SwissProt-2: P08226
Organism-3: Rat
Gene ID-3: 25728
SwissProt-3: P02650
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Secreted . Secreted, extracellular space . Secreted, extracellular space, extracellular matrix . In the plasma, APOE is associated with chylomicrons, chylomicrons remnants, VLDL, LDL and HDL lipoproteins (PubMed:1911868, PubMed:8340399). Lipid poor oligomeric APOE is associated with the extracellular matrix in a calcium- and heparan-sulfate proteoglycans-dependent manner (PubMed:9488694). Lipidation induces the release from the extracellular matrix (PubMed:9488694). .