- Target
- ALY
- Reactivity
- Human,Mouse,Rat
- Application
- WB,ELISA
- MW(Calculated)
- --
- MW(Observed)
- 27kD
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- The antiserum was produced against synthesized peptide derived from human THOC4. AA range:121-170
- Sequence
- --
- Specificity
- ALY Polyclonal Antibody detects endogenous levels of ALY protein.
- Gene Name
- ALYREF
- Protein Name
- THO complex subunit 4
- Other Name
- ALYREF;ALY;BEF;THOC4;THO complex subunit 4;Tho4;Ally of AML-1 and LEF-1;Aly/REF export factor;Transcriptional coactivator Aly/REF;bZIP-enhancing factor BEF
- Organism-1
- Human
- Gene ID-1
- 10189
- SwissProt-1
- Q86V81
- Organism-2
- Mouse
- Gene ID-2
- 21681
- SwissProt-2
- O08583
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Nucleus . Nucleus speckle . Cytoplasm . Colocalizes with the core EJC, ALYREF/THOC4, NXF1 and DDX39B in the nucleus and nuclear speckles. Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA (PubMed:19324961). Localizes to regions surrounding nuclear speckles known as perispeckles in which TREX complex assembly seems to occur (PubMed:23826332). .