- Target
- A1Up
- Reactivity
- Human,Mouse
- Application
- WB,IHC,IF,ELISA
- MW(Calculated)
- --
- MW(Observed)
- 54kD
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- The antiserum was produced against synthesized peptide derived from human UBQLN4. AA range:201-250
- Sequence
- --
- Specificity
- A1Up Polyclonal Antibody detects endogenous levels of A1Up protein.
- Gene Name
- UBQLN4
- Protein Name
- Ubiquilin-4
- Other Name
- UBQLN4;C1orf6;CIP75;UBIN;Ubiquilin-4;Ataxin-1 interacting ubiquitin-like protein;A1Up;Ataxin-1 ubiquitin-like-interacting protein A1U;Connexin43-interacting protein of 75 kDa;CIP75
- Organism-1
- Human
- Gene ID-1
- 56893
- SwissProt-1
- Q9NRR5
- Organism-2
- Mouse
- Gene ID-2
- 94232
- SwissProt-2
- Q99NB8
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Nucleus . Cytoplasm . Chromosome . Endoplasmic reticulum . Cytoplasm, perinuclear region . Cytoplasmic vesicle, autophagosome . Colocalizes with the proteasome, both in nucleus and cytoplasm (PubMed:15280365). Exported from the nucleus following interaction with DESI1/POST (PubMed:29666234). In response to DNA damage and phosphorylation at Ser-318 by ATM, localizes to the nucleus and is recruited to sites of DNA damage (PubMed:30612738). .