U-Blot® 14-3-3 ε Polyclonal Antibody

Name: U-Blot® 14-3-3 ε Polyclonal Antibody
SKU: WP10845
Availability: InStock

$268.00

Size:50μL

SKU: WP10845-50

Catalog No.: WP10845

Specification: 50μL/100μL

Stock: In stock

U-Blot® 14-3-3 ε Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008],

Product Overview

Catalog No.: WP10845
SKU: WP10845-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: 14-3-3 ε
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 29kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human 14-3-3 epsilon. AA range:206-255
Sequence: --
Specificity: 14-3-3 ε Polyclonal Antibody detects endogenous levels of 14-3-3 ε protein.
Gene Name: YWHAE
Protein Name: 14-3-3 protein epsilon
Other Name: YWHAE;14-3-3 protein epsilon;14-3-3E
Organism-1: Human
Gene ID-1: 7531
SwissProt-1: P62258
Organism-2: Mouse
Gene ID-2: 22627
SwissProt-2: P62259
Organism-3: Rat
Gene ID-3: 29753
SwissProt-3: P62260
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Cytoplasm . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .