U-Blot® DNA2 Polyclonal Antibody

Name: U-Blot® DNA2 Polyclonal Antibody
SKU: WP1077
Availability: InStock

$268.00

Size:50μL

SKU: WP1077-50

Catalog No.: WP1077

Specification: 50μL/100μL

Stock: In stock

U-Blot® DNA2 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a member of the DNA2/NAM7 helicase family. The encoded protein is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014],

Product Overview

Catalog No.: WP1077
SKU: WP1077-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: DNA2
Reactivity: Human,Mouse
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 116kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from part region of human protein
Sequence: --
Specificity: DNA2 Polyclonal Antibody detects endogenous levels of protein.
Gene Name: DNA2 DNA2L KIAA0083
Protein Name: DNA replication ATP-dependent helicase/nuclease DNA2 (hDNA2) (DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)]
Other Name: --
Organism-1: Human
Gene ID-1: 1763
SwissProt-1: P51530
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q6ZQJ5
Organism-3: Rat
Gene ID-3: --
SwissProt-3: D3ZG52
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus. Mitochondrion. Was initially reported to be exclusively mitochondrial (PubMed:18995831). However, it was later shown to localize both in mitochondrion and nucleus (PubMed:19487465). .