- Target
- TORC1
- Reactivity
- Human,Rat,Mouse,
- Application
- WB
- MW(Calculated)
- --
- MW(Observed)
- 70kD
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Phospho
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:1000-2000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized phosho peptide around human TORC1 and CRTC1 (Ser151)
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of Human TORC1 or CRTC1 (phospho-Ser151)
- Gene Name
- CRTC1 KIAA0616 MECT1 TORC1 WAMTP1
- Protein Name
- TORC1/CRTC1 (Ser151)
- Other Name
- CRTC1;KIAA0616;MECT1;TORC1;WAMTP1;CREB-regulated transcription coactivator 1;Mucoepidermoid carcinoma translocated protein 1;Transducer of regulated cAMP response element-binding protein 1;TORC-1;Transducer of CREB protein 1
- Organism-1
- Human
- Gene ID-1
- 23373
- SwissProt-1
- Q6UUV9
- Organism-2
- Mouse
- Gene ID-2
- 382056
- SwissProt-2
- Q68ED7
- Organism-3
- Rat
- Gene ID-3
- 684527
- SwissProt-3
- Q157S1
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cytoplasm . Nucleus . Cytoplasmic when phosphorylated by SIK or AMPK and when sequestered by 14-3-3 proteins (PubMed:16817901). Translocated to the nucleus on Ser-151 dephosphorylation, instigated by a number of factors including calcium ion and cAMP levels (PubMed:15589160). Light stimulation triggers a nuclear accumulation in the suprachiasmatic nucleus (SCN) of the brain (By similarity). .