U-Blot® Scribble (Phospho Ser1220) rabbit pAb

Name: U-Blot® Scribble (Phospho Ser1220) rabbit pAb
SKU: WP10482
Availability: InStock

$288.00

Size:50μL

SKU: WP10482-50

Catalog No.: WP10482

Specification: 50μL/100μL

Stock: In stock

U-Blot® Scribble (Phospho Ser1220) rabbit pAb Learn more

Product details Specifications Q & A Education

Background：This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011],

Product Overview

Catalog No.: WP10482
SKU: WP10482-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: SCRIB
Reactivity: Human,Mouse
Application: WB,ELISA,IHC
MW(Calculated): --
MW(Observed): 179kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Phospho
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized phosho peptide around human Scribble (Ser1220)
Sequence: --
Specificity: This antibody detects endogenous levels of Human Mouse Scribble (phospho-Ser1220)
Gene Name: SCRIB CRIB1 KIAA0147 LAP4 SCRB1 VARTUL
Protein Name: Protein scribble homolog
Other Name: Protein scribble homolog;Scribble;hScrib;Protein LAP4;
Organism-1: Human
Gene ID-1: 23513
SwissProt-1: Q14160
Organism-2: Mouse
Gene ID-2: 105782
SwissProt-2: Q80U72
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane ; Peripheral membrane protein. Cell junction . Cell junction, adherens junction. Cell projection, lamellipodium. Cytoplasm. Cell junction, synapse, postsynapse . Cell junction, synapse, presynapse . Targeting to cell-cell junctions which is CDH1-dependent is required for the pro-apoptotic activity. In a subset of CD4+ T-cells, colocalizes with CRTAM at the immunological synapse during the late phase of T-cell activation (By similarity). .