Product information
Background:The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008],
Product Overview
- Catalog No.
- WP10472
- SKU
- WP10472-50
- Category
- Polyclonal antibodies
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- RIP3
- Reactivity
- Human
- Application
- WB,ELISA,IHC
- MW(Calculated)
- --
- MW(Observed)
- 56-70kD
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Phospho
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized phosho peptide around human RIP3 (Ser227)
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of Human RIP3 (phospho-Ser227)
- Gene Name
- RIPK3 RIP3
- Protein Name
- RIP3 (Ser227)
- Other Name
- Receptor-interacting serine/threonine-protein kinase 3;RIP-like protein kinase 3;Receptor-interacting protein 3;RIP-3;
- Organism-1
- Human
- Gene ID-1
- 11035
- SwissProt-1
- Q9Y572
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- Q9QZL0
- Organism-3
- Rat
- Gene ID-3
- 246240
- SwissProt-3
- Q9Z2P5
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cytoplasm, cytosol . Nucleus . Mainly cytoplasmic. Present in the nucleus in response to influenza A virus (IAV) infection. .
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)