Product information
Background:The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008],
Product Overview
- Catalog No.
- WP10392
- SKU
- WP10392-50
- Category
- Polyclonal antibodies
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- JAK3
- Reactivity
- Human,Mouse
- Application
- WB,IHC
- MW(Calculated)
- --
- MW(Observed)
- 125kD
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Phospho
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000;IHC 1:50-300
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized phosho peptide around human Jak3 (Tyr980 and 981)
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of Human Mouse Jak3 (phospho-Tyr980 or 981)
- Gene Name
- JAK3
- Protein Name
- Jak3 (Tyr980/981)
- Other Name
- Tyrosine-protein kinase JAK3;Janus kinase 3;JAK-3;Leukocyte janus kinase;L-JAK;
- Organism-1
- Human
- Gene ID-1
- 3718
- SwissProt-1
- P52333
- Organism-2
- Mouse
- Gene ID-2
- 16453
- SwissProt-2
- Q62137
- Organism-3
- Rat
- Gene ID-3
- --
- SwissProt-3
- Q63272
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Endomembrane system ; Peripheral membrane protein . Cytoplasm .
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)