Product information
Background:docking protein 2(DOK2) Homo sapiens The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008],
Product Overview
- Catalog No.
- WP10144
- SKU
- WP10144-50
- Category
- Polyclonal antibodies
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- Dok-2
- Reactivity
- Human,Mouse
- Application
- IHC,IF,ELISA
- MW(Calculated)
- 45kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Phospho
- Modification site
- --
- Recommended Dilution Ratio
- IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized phospho-peptide around the phosphorylation site of human Dok-2 (phospho Tyr345)
- Sequence
- --
- Specificity
- Phospho-Dok-2 (Y345) Polyclonal Antibody detects endogenous levels of Dok-2 protein only when phosphorylated at Y345.
- Gene Name
- DOK2
- Protein Name
- Docking protein 2
- Other Name
- DOK2;Docking protein 2;Downstream of tyrosine kinase 2;p56;dok-2;
- Organism-1
- Human
- Gene ID-1
- 9046
- SwissProt-1
- O60496
- Organism-2
- Mouse
- Gene ID-2
- 13449
- SwissProt-2
- O70469
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- cytosol,
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)