Product information
Background:This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, May 2011],
Product Overview
- Catalog No.
- WP0994
- SKU
- WP0994-50
- Category
- Polyclonal antibodies
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- MPRD
- Reactivity
- Human,Mouse,Rat
- Application
- WB,ELISA
- MW(Calculated)
- --
- MW(Observed)
- 30kD
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000;ELISA 1:5000-20000
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from part region of human protein
- Sequence
- --
- Specificity
- MPRD Polyclonal Antibody detects endogenous levels of protein.
- Gene Name
- M6PR MPR46 MPRD
- Protein Name
- Cation-dependent mannose-6-phosphate receptor (CD Man-6-P receptor) (CD-MPR) (46 kDa mannose 6-phosphate receptor) (MPR 46)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 4074
- SwissProt-1
- P20645
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- P24668
- Organism-3
- Rat
- Gene ID-3
- --
- SwissProt-3
- Q6AY20
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Lysosome membrane; Single-pass type I membrane protein.
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)