Product information
Background:This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
Product Overview
- Catalog No.
- WP0691
- SKU
- WP0691-50
- Category
- Polyclonal antibodies
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- MX1
- Reactivity
- Human,Rat
- Application
- WB,ELISA
- MW(Calculated)
- --
- MW(Observed)
- 72kD
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000;ELISA 1:5000-20000
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human protein . at AA range: 500-580
- Sequence
- --
- Specificity
- MX1 Polyclonal Antibody detects endogenous levels of protein.
- Gene Name
- MX1
- Protein Name
- Interferon-induced GTP-binding protein Mx1 (Interferon-induced protein p78) (IFI-78K) (Interferon-regulated resistance GTP-binding protein MxA) (Myxoma resistance protein 1) (Myxovirus resistance protein 1)
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 4599
- SwissProt-1
- P20591
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- P09922
- Organism-3
- Rat
- Gene ID-3
- --
- SwissProt-3
- P18588
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cytoplasm . Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side. Cytoplasm, perinuclear region . Binds preferentially to negatively charged phospholipids (PubMed:21900240). Colocalizes with CCHFV protein N in the perinuclear region (PubMed:15047845). .; [Isoform 2]: Cytoplasm . Nucleus . Translocates into the nuclei of HSV-1 infected cells (PubMed:20603636). .
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Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
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Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)