Product information
Background:The protein encoded by this gene is a secreted blood zymogen that is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in this gene are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009],
Product Overview
- Catalog No.
- WP0095
- SKU
- WP0095-50
- Category
- Polyclonal antibodies
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- Plasminogen HC A
- Reactivity
- Human,Mouse,Rat
- Application
- WB,ELISA
- MW(Calculated)
- --
- MW(Observed)
- 54kD
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- The antiserum was produced against synthesized peptide derived from human PLMN. AA range:79-128
- Sequence
- --
- Specificity
- Cleaved-Plasminogen HC A short form (V98) Polyclonal Antibody detects endogenous levels of fragment of activated Plasminogen HC A short form protein resulting from cleavage adjacent to V98.
- Gene Name
- PLG
- Protein Name
- Plasminogen
- Other Name
- PLG;Plasminogen
- Organism-1
- Human
- Gene ID-1
- 5340
- SwissProt-1
- P00747
- Organism-2
- Mouse
- Gene ID-2
- 18815
- SwissProt-2
- P20918
- Organism-3
- Rat
- Gene ID-3
- 85253
- SwissProt-3
- Q01177
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Secreted . Locates to the cell surface where it is proteolytically cleaved to produce the active plasmin. Interaction with HRG tethers it to the cell surface.
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)