Product information
Background:CD183, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes, or granulocytes.
Product Overview
- Catalog No.
- WN0589
- SKU
- WN0589
- Category
- Nanobodies
- Product Type
- Other
- Size
- 100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- Research Use Only
- Yes
Additional Specifications
- Target
- CD183
- Reactivity
- Human
- Application
- ELISA
- MW(Calculated)
- --
- MW(Observed)
- --
- Host Species
- Camel
- Isotype
- --
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- ELISA 1:5000-100000
- Form
- Phosphate-buffered solution
- Source
- Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
- Purification
- Recombinant Expression and Affinity purified
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- Concentration
- Please check the information on the tube
- Clonality
- Monoclonal
- Clone No.
- PN0091
- Immunogen
- Purified recombinant Human CD183
- Sequence
- --
- Specificity
- This recombinant monoclonal antibody can detects endogenous levels of CD183 protein.
- Gene Name
- CXCR3 GPR9
- Protein Name
- C-X-C chemokine receptor type 3 (CXC-R3) (CXCR-3) (CKR-L2) (G protein-coupled receptor 9) (Interferon-inducible protein 10 receptor) (IP-10 receptor) (CD antigen CD183)
- Other Name
- GFP nanobody;
- Organism-1
- Human
- Gene ID-1
- 2833
- SwissProt-1
- P49682
- Organism-2
- --
- Gene ID-2
- --
- SwissProt-2
- --
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- [Isoform 1]: Cell membrane ; Multi-pass membrane protein .; [Isoform 2]: Cell membrane ; Multi-pass membrane protein .
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)