Product information
Background:The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008],
Product Overview
- Catalog No.
- WM1856
- SKU
- WM1856-50
- Category
- Mouse mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Research Use Only
- Yes
Additional Specifications
- Target
- Fas
- Reactivity
- Human
- Application
- FC,IF
- MW(Calculated)
- --
- MW(Observed)
- --
- Host Species
- Mouse
- Isotype
- Mouse IgG1/Kappa
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- IF 1:200-1:1000;FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application
- Form
- PBS, pH 7.4
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Concentration
- 0.5mg/ml
- Clonality
- Monoclonal
- Clone No.
- PTF0126
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- FAS
- Protein Name
- Tumor necrosis factor receptor superfamily member 6
- Other Name
- FAS;APT1;FAS1;TNFRSF6;Tumor necrosis factor receptor superfamily member 6;Apo-1 antigen;Apoptosis-mediating surface antigen FAS;FASLG receptor;CD95
- Organism-1
- Human
- Gene ID-1
- 8685
- SwissProt-1
- Q9UEW3
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- Q60754
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Isoform 1 and isoform 6 are expressed at equal levels in resting peripheral blood mononuclear cells. After activation there is an increase in isoform 1 and decrease in the levels of isoform 6.
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.