Product information
Background:The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. [provided by RefSeq, Dec 2015],
Product Overview
- Catalog No.
- WM1840
- SKU
- WM1840-50
- Category
- Mouse mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Research Use Only
- Yes
Additional Specifications
- Target
- IL-7R
- Reactivity
- Human
- Application
- FC,IF
- MW(Calculated)
- 52kD
- MW(Observed)
- 70kD
- Host Species
- Mouse
- Isotype
- Mouse IgG1/Kappa
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:4000-1:20000;IF 1:200-1:1000;FC:1 µg per million cells in 100 µl volume. For optimal results, the reagent should be titrated according to each specific application
- Form
- PBS, pH 7.4
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- PTF0044
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- IL7R
- Protein Name
- Interleukin-7 receptor subunit alpha
- Other Name
- IL7R;Interleukin-7 receptor subunit alpha;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL-7RA;CDw127;CD antigen CD127
- Organism-1
- Human
- Gene ID-1
- 3575
- SwissProt-1
- P16871
- Organism-2
- --
- Gene ID-2
- --
- SwissProt-2
- --
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell membrane; Single-pass type I membrane protein.; [Isoform 4]: Secreted.
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.