Product information
Background:This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. [provided by RefSeq, Oct 2009],
Product Overview
- Catalog No.
- WM1815
- SKU
- WM1815-50
- Category
- Mouse mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- CKR-4
- Reactivity
- Human
- Application
- IF,WB
- MW(Calculated)
- 41kD
- MW(Observed)
- 37kD
- Host Species
- Mouse
- Isotype
- Mouse IgG1/Kappa
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:1000-1:5000;IF 1:200-1:1000;
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- PTR1475
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- CCR4
- Protein Name
- C-C chemokine receptor type 4
- Other Name
- CCR4;CMKBR4;C-C chemokine receptor type 4;C-C CKR-4;CC-CKR-4;CCR-4;CCR4;K5-5;CD194
- Organism-1
- Human
- Gene ID-1
- 5732
- SwissProt-1
- P43116
- Organism-2
- Mouse
- Gene ID-2
- 19217
- SwissProt-2
- Q62053
- Organism-3
- Rat
- Gene ID-3
- 81752
- SwissProt-3
- Q62928
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Predominantly expressed in the thymus, in peripheral blood leukocytes, including T-cells, mostly CD4+ cells, and basophils, and in platelets; at lower levels, in the spleen and in monocytes. Detected also in macrophages, IL-2-activated natural killer cells and skin-homing memory T-cells, mostly the ones expressing the cutaneous lymphocyte antigen (CLA). Expressed in brain microvascular and coronary artery endothelial cells.
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)