Product information
Background:Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.[provided by RefSeq, Jul 2010],
Product Overview
- Catalog No.
- WM1813
- SKU
- WM1813-50
- Category
- Mouse mAbs
- Product Type
- Other
- Size
- 50μL/100μL
- Stock Status
- In stock
- Available Stock
- 20
- Minimum Order Quantity
- 1
Storage & Compliance
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Research Use Only
- Yes
Additional Specifications
- Target
- CD326/EPCAM
- Reactivity
- Human
- Application
- IF,IHC
- MW(Calculated)
- --
- MW(Observed)
- --
- Host Species
- Mouse
- Isotype
- Mouse IgG2b/Kappa
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- IHC 1:500-1:1000;;IF 1:200-1:1000;
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- Protein A
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- --
- Clonality
- Monoclonal
- Clone No.
- PTR1473
- Immunogen
- --
- Sequence
- --
- Specificity
- Endogenous
- Gene Name
- EPCAM GA733-2 M1S2 M4S1 MIC18 TACSTD1 TROP1
- Protein Name
- Epithelial cell adhesion molecule
- Other Name
- 17 1A;323/A3;Adenocarcinoma associated antigen;Adenocarcinoma-associated antigen;Antigen identified by monoclonal antibody AUA1;AUA1;CD326;CD326 antigen;Cell surface glycoprotein Trop 1;Cell surface glycoprotein Trop 2;Cell surface glycoprotein Trop-1;CO 17A;CO17 1A;CO17A;DIAR5;EGP 2;EGP;EGP2;EGP314;EGP40;Ep CAM;Ep-CAM;EPCAM;EPCAM_HUMAN;Epithelial cell adhesion molecule;Epithelial Cell Adhesion Molecule Intracellular Domain;EpCAM-ICD;Epithelial cell surface antigen;Epithelial cellular adhesion molecule;Epithelial glycoprotein 1;Epithelial glycoprotein 314;Epithelial glycoprotein;ESA;GA733 1;GA733 2;GA733-2;gastrointestinal tumor-associated antigen 2;35-KD glycoprotein;hEGP 2;hEGP314;HNPCC8;Human epithelial glycoprotein 2;KS 1/4 antigen;KS1/4;KSA;Lymphocyte antigen 74;M1S 1;M1S2;M4S1;Major gastrointestinal tumor associated protein GA733 2;Major gastrointestinal tumor-associated protein GA733-2;Membrane component chromosome 4 surface marker;35kD glycoprotein;Membrane component;chromosome 4;surface marker 1;Membrane component;chromosome 4;surface marker;MIC18;MK 1;TACD1;TACSTD1;TROP1;Tumor associated calcium signal transducer 1;Tumor associated calcium signal transducer 2 precursor;Tumor-associated calcium signal transducer 1;CD326 nanobody;EPCAM nanobody;
- Organism-1
- Human
- Gene ID-1
- 5293
- SwissProt-1
- O00329
- Organism-2
- Mouse
- Gene ID-2
- 18707
- SwissProt-2
- O35904
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma.
01
Documents
Datasheet, COA, SDS, and protocol files can be requested from technical support.
02
Storage & Handling
- Storage
- -15°C to -25°C/1 year(Do not lower than -25°C)